Perineural Spread in Head and Neck Cancer: Current Perspectives
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چکیده
Perineural spread is mechanism of tumor dissemination along a nerve in the head and neck with decreased survival and a higher risk of local recurrence and metastasis. Even though several theories have been proposed, pathogenesis of perineural spread is poorly understood. Advances in diagnostic imaging and the development of new fronts like skull base surgery have brought a transcending change in the treatment of perineural spread in head and neck cancer. Present review is an attempt to discuss pathogenesis, pathways of spread, various diagnostic modalities and treatment protocol.
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تاریخ انتشار 2016